One of the most obvious sources of guilt is Lady Macbeth's downfall. In the first scene of the fifth act, Lady Macbeth enters the scene, but not as the assertive woman at the beginning of the play. Lady Macbeth begins to suffer from sleepwalking and her health slowly begins to deteriorate. Ironically, just as she was telling her husband to wash away the guilt at the beginning of the play, she begins to "wash her arms" and says "Get out of the damn place! Get out, I say!" And also "But who would have thought that the old man had so much blood in his body?" (Act 5, scene 1, lines 30-34). I personally believe that the blood she talks about is a reference to her guilt and shame and she feels the only way to get rid of it is to "wash" it and "rub it away". She also refers to King Duncan as the old man, the only person who gave her trouble. "The lord of life had a wife. Where is she now? How, these hands will never be clean?" (). After continually massaging her arm, Lady Macbeth cries, "You still smell the blood. All the scents of Arabia will not sweeten this little hand." (). Lady Macbeth finally realizes that she cannot give up the guilt associated with the murders. I think he really feels responsible for the murders that Macbeth commits and a couple of scenes later he gives up his life. This action could be interpreted as Lady Macbeth's breaking point from all feelings of guilt and blame